Description

(S)-4-(1-Hydroxymethyl-Propylamino)Benzaldehyde is a chiral, functionalized benzaldehyde derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and high-value pharmaceutical intermediate and chiral building block for constructing complex molecules with specific stereochemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring enantiomerically pure molecules.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material in catalytic asymmetric reactions to introduce stereogenic centers.
• Ligand and Catalyst Development: Used in the research and preparation of novel chiral ligands for metal-catalyzed transformations.
• Agrochemical Synthesis: Building block for developing enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, and fragrances where optical purity is critical.
• Academic and Industrial Research: Valuable reagent for methodological studies in organic chemistry and process chemistry optimization.

Basic Information

Product Name	(S)-4-(1-Hydroxymethyl-Propylamino)Benzaldehyde
CAS No.	572923-24-1
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	(S)-4-[(1-Hydroxymethyl-propyl)amino]benzaldehyde; (S)-p-[(1-Hydroxymethylpropyl)amino]benzaldehyde; Benzaldehyde, 4-[(1S)-1-(hydroxymethyl)propyl]amino]-; (S)-4-Amino-α-ethylbenzenemethanol, 4-formyl derivative; (S)-1-(4-Formylphenylamino)butan-2-ol; (S)-4-(1-Hydroxybutan-2-ylamino)benzaldehyde
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chiral intermediates. Production follows current Good Manufacturing Practice (GMP) principles where applicable, ensuring traceability and consistency. Every batch is characterized by advanced analytical techniques including HPLC for chiral purity and assay, NMR for structural confirmation, and optical rotation measurement. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This material is easily oxidized and light-sensitive. Allow the container to reach ambient temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.