Description

(S)-4-Methyl-3-(4-Trifluoromethylphenyl)Oxazolidin-2-One CAS NO 572922-96-4 is a high-value, chiral oxazolidinone derivative characterized by its trifluoromethylphenyl substituent. This compound serves as a critical chiral auxiliary and synthetic intermediate in modern asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and agrochemicals. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in their synthetic routes.

Application

• As a chiral auxiliary in asymmetric aldol, alkylation, and Diels-Alder reactions.
• Key synthetic intermediate for the development of novel active pharmaceutical ingredients (APIs).
• Building block for agrochemical research, particularly in creating compounds with enhanced biological activity and selectivity.
• Use in academic and industrial R&D for methodological studies in stereoselective synthesis.
• Precursor for ligands and catalysts used in enantioselective transformations.
• Intermediate in the synthesis of complex natural products and specialty chemicals.

Basic Information

Item	Detail
Product Name	(S)-4-Methyl-3-(4-Trifluoromethylphenyl)Oxazolidin-2-One
CAS No.	572922-96-4
Molecular Formula	C11H10F3NO2
Molecular Weight	245.20 g/mol
Synonyms	(S)-4-Methyl-3-[4-(trifluoromethyl)phenyl]-2-oxazolidinone; (4S)-4-Methyl-3-[4-(trifluoromethyl)phenyl]-1,3-oxazolidin-2-one; (S)-4-Methyl-3-(4-trifluoromethylphenyl)oxazolidin-2-one; (S)-3-(4-Trifluoromethylphenyl)-4-methyloxazolidin-2-one; (S)-TFBO; Evans Auxiliary derivative; Chiral oxazolidinone auxiliary
EINECS	Contact for details

Quality Control

Our (S)-4-Methyl-3-(4-Trifluoromethylphenyl)Oxazolidin-2-One is manufactured under strict quality control protocols to ensure high chemical and chiral purity, meeting the exacting standards for advanced synthetic applications. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.