Description

2-Methyl-5-Bromobiphenyl is a high-purity brominated biphenyl derivative, a key organic intermediate valued for its role in advanced synthesis. This compound is essential for constructing complex molecular architectures, particularly in the development of pharmaceuticals and functional materials. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in cross-coupling reactions and ligand synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging its biphenyl core for bioactivity.
• Material Science: Serves as a precursor for organic light-emitting diodes (OLEDs) and liquid crystal (LC) materials, where its structure contributes to desired electronic properties.
• Catalyst & Ligand Development: Employed in the creation of sophisticated phosphine or N-heterocyclic carbene (NHC) ligands for transition metal catalysis.
• Cross-Coupling Reactions: Functions as a versatile substrate in Suzuki, Negishi, and other palladium-catalyzed cross-coupling reactions to form complex biaryl systems.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and scale-up process development.

Basic Information

Item	Detail
Product Name	2-Methyl-5-Bromobiphenyl
CAS No.	571903-41-8
Molecular Formula	C13H11Br
Molecular Weight	247.13 g/mol
Synonyms	5'-Bromo-2-methylbiphenyl; 2-Methyl-5'-bromobiphenyl; 1-Bromo-4-(2-methylphenyl)benzene; 5-Bromo-2'-methylbiphenyl; (2-Methylphenyl)-4-bromobenzene; 4-Bromo-2'-methyl-1,1'-biphenyl; 2-Methyl-5-bromobiphenyl; 2'-Methyl-5-bromobiphenyl
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-5-Bromobiphenyl is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency that meets the stringent requirements of industrial and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.