Description

2,2,2-Trifluoro-n-(3-Morpholin-4-Yl-Propyl)-Acetamide is a specialized fluorinated acetamide derivative featuring a morpholine-propyl side chain, offering unique reactivity and physicochemical properties. This compound is a valuable high-purity building block for advanced chemical synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily targeted at pharmaceutical R&D and fine chemical manufacturing sectors where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, or insecticides where the trifluoroacetamide and morpholine groups contribute to biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis or as a component in organometallic complexes.
• Material Science Research: Employed in the synthesis of functional polymers or advanced materials where fluorine atoms impart desirable properties like oleophobicity or chemical resistance.
• Chemical Biology Probe: Utilized in the design of molecular probes for studying enzyme mechanisms or protein interactions due to its potential as a bioisostere.

Basic Information

Product Name	2,2,2-Trifluoro-n-(3-Morpholin-4-Yl-Propyl)-Acetamide
CAS No.	570421-58-8
Molecular Formula	C9H15F3N2O2
Molecular Weight	240.22 g/mol
Synonyms	N-(3-Morpholinopropyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-[3-(4-morpholinyl)propyl]acetamide; 3-Morpholin-4-yl-propyl-trifluoroacetamide; 2,2,2-Trifluoroacetamide, N-[3-(4-morpholinyl)propyl]-; 570421-58-8; Trifluoroacetamide morpholine derivative; N-(3-Morpholinopropyl)trifluoroacetamide
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-n-(3-Morpholin-4-Yl-Propyl)-Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and fine chemical applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.