Description

1H-2-Benzopyran-4,5-Diol, 3,4-Dihydro-8-Methoxy-1,3-Dimethyl-, (1R,3S,4R)-Rel- (9Ci) is a high-purity, stereochemically defined chroman derivative. This compound serves as a critical chiral building block and synthetic intermediate for advanced pharmaceutical research and fine chemical synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients with specific stereochemical configurations.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new chemical entities (NCEs), particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Serves as a versatile starting material or precursor in catalytic asymmetric reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its defined stereochemistry and functional groups.
• Agrochemical Development: Potential intermediate in the synthesis of novel, stereoselective pesticides and plant growth regulators.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic Research: A valuable compound for methodological studies in organic synthesis and catalysis at universities and research institutes.

Basic Information

Item	Details
Product Name	1H-2-Benzopyran-4,5-Diol, 3,4-Dihydro-8-Methoxy-1,3-Dimethyl-, (1R,3S,4R)-Rel- (9Ci)
CAS No.	569652-83-1
Molecular Formula	C12H16O4
Molecular Weight	224.25 g/mol
Synonyms	rel-(1R,3S,4R)-3,4-Dihydro-8-methoxy-1,3-dimethyl-1H-2-benzopyran-4,5-diol; 3,4-Dihydro-8-methoxy-1,3-dimethyl-1H-2-benzopyran-4,5-diol, (1R,3S,4R)-rel-; Chroman-4,5-diol derivative; 8-Methoxy-1,3-dimethylchroman-4,5-diol (relative configuration); (rel)-(1R,3S,4R)-8-Methoxy-1,3-dimethyl-3,4-dihydro-1H-2-benzopyran-4,5-diol
EINECS	Contact for details

Quality Control

Our 1H-2-Benzopyran-4,5-Diol, 3,4-Dihydro-8-Methoxy-1,3-Dimethyl-, (1R,3S,4R)-Rel- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates. Specifications can be customized to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. For long-term storage, consider using an inert atmosphere (e.g., nitrogen or argon) to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.