Description

(-)Menthone1,2-Glycerolketal is a high-purity, specialized ketal derivative of (-)-menthone. This compound is valued for its role as a versatile chiral intermediate and building block in advanced organic synthesis. It is primarily sought after by research and development laboratories, flavor and fragrance houses, and pharmaceutical manufacturers for creating complex molecules with specific stereochemistry.

Application

• Flavor and Fragrance Synthesis: Serves as a key chiral intermediate for creating novel cooling agents, minty notes, and complex aroma chemicals.
• Pharmaceutical Intermediates: Used in the research and development of active pharmaceutical ingredients (APIs) where the specific stereochemistry of the menthone backbone is required.
• Asymmetric Synthesis: Acts as a chiral auxiliary or building block in stereoselective reactions to induce desired optical activity in target molecules.
• Organic Chemistry Research: Employed in academic and industrial R&D for studying ketal chemistry, protecting group strategies, and terpene transformations.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals for agrochemicals, cosmetics, and other high-value applications.

Basic Information

Product Name	(-)Menthone1,2-Glycerolketal
CAS No.	563187-91-7
Molecular Formula	C₁₃H₂₄O₃
Molecular Weight	228.33 g/mol
Synonyms	(-)-Menthone Glycerol Ketal; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanone 1,2-Glycerol Ketal; L-Menthone Glycerol Ketal; (4R,7S)-4-Isopropyl-7-methyl-1,3-dioxaspiro[4.5]decan-2-ol; Menthone Glycerin Ketal; (-)-Menthone cyclic glycerol ketal; 1,2-O-Isopropylidene-3-O-[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]glycerol
EINECS	Contact for details

Quality Control

Our (-)Menthone1,2-Glycerolketal is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC and structural confirmation by NMR and IR spectroscopy, to ensure high chemical and optical purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.