Description

4-tert-Butylcyclohexanone Diethyl Acetal is a high-purity specialty chemical intermediate, valued for its role as a protected carbonyl synthon in complex organic synthesis. Its primary commercial importance lies in enabling precise, multi-step reactions for the production of fine chemicals and advanced materials. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fragrance industries seeking to build complex molecular architectures with high selectivity.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for steroidal and terpenoid-based compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the tert-butylcyclohexyl moiety imparts specific biological activity.
• Fragrance and Flavor Ingredient: Acts as a precursor for musky and woody aroma chemicals, leveraging the stability of the acetal group during synthesis.
• Organic Synthesis Reagent: Functions as a versatile protecting group for ketones in multi-step synthetic pathways, preventing unwanted side reactions.
• Material Science Research: Employed in the development of novel polymers and liquid crystals where the bulky tert-butyl group influences material properties.
• Chemical Research & Development: A valuable tool for academic and industrial chemists exploring new methodologies in asymmetric synthesis and catalysis.

Basic Information

Product Name	4-tert-Butylcyclohexanone Diethyl Acetal
CAS No.	1900-58-9
Molecular Formula	C₁₄H₂₈O₂
Molecular Weight	228.37 g/mol
Synonyms	4-(1,1-Dimethylethyl)cyclohexanone Diethyl Acetal; 4-tert-Butylcyclohexanone Diethyl Ketal; Diethyl (4-tert-butylcyclohexylidene) Orthoacetate; 1,1-Diethoxy-4-tert-butylcyclohexane; NSC 403697; 4-tert-Butylcyclohexanone Diethyl Acetal; 4-tert-Butylcyclohexylidene Diethyl Acetal
EINECS	217-606-7

Quality Control

Our 4-tert-Butylcyclohexanone Diethyl Acetal is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.450 - 1.455
Density (20°C)	0.90 - 0.95 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.