Description

2,2-Dimethyl-2'-Fluoropropiophenone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring a tertiary butyl-like group adjacent to the carbonyl and a fluorine substituent on the aromatic ring, makes it a valuable precursor for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries. It serves as a critical intermediate for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, or organic electronic materials with specific optical or electronic properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex molecular architectures via reactions like Friedel-Crafts acylation, nucleophilic addition, or cross-coupling.
• Fluorine Chemistry Studies: A valuable compound for investigating structure-activity relationships (SAR) and the influence of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	2,2-Dimethyl-2'-Fluoropropiophenone
CAS No.	560085-36-1
Molecular Formula	C11H13FO
Molecular Weight	180.22 g/mol
Synonyms	2'-Fluoro-2,2-dimethylpropiophenone; 1-(2-Fluorophenyl)-2,2-dimethylpropan-1-one; α,α-Dimethyl-2-fluorophenyl methyl ketone; 2-Fluoro-α,α-dimethylacetophenone; 2,2-Dimethyl-1-(2-fluorophenyl)propan-1-one; Propiophenone, 2,2-dimethyl-2'-fluoro-; 2-Fluorophenyl tert-butyl ketone
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-2'-Fluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.