Description

Oxiranecarbonitrile, 3-(4-Fluorophenyl)-, (2R,3R)-Rel- (9Ci) is a high-value chiral epoxide building block, specifically the (2R,3R)-rel enantiomer, critical for the synthesis of complex, optically active molecules. Its core value lies in providing a defined stereochemical handle to introduce both a fluorinated aromatic moiety and a reactive nitrile group in a single, controlled step. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who require precise stereochemistry for developing new active ingredients. Its application is pivotal in constructing chiral intermediates for potential drug candidates and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure herbicides, fungicides, and insecticides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Asymmetric Catalysis Research: Serves as a standard substrate or ligand precursor in academic and industrial research focused on developing new asymmetric synthetic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fluorinated fine chemicals and specialty materials requiring high stereochemical fidelity.
• Liquid Crystal & OLED Material Precursor: Acts as a building block for creating chiral, fluorinated components used in advanced display technologies and organic electronics.

Basic Information

Product Name	Oxiranecarbonitrile, 3-(4-Fluorophenyl)-, (2R,3R)-Rel- (9Ci)
CAS No.	556053-57-7
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	rel-(2R,3R)-3-(4-Fluorophenyl)oxiranecarbonitrile; (2R,3R)-rel-3-(4-Fluorophenyl)glycidonitrile; 4-Fluorophenylglycidonitrile, (2R,3R)-rel-; (R*,R*)-3-(p-Fluorophenyl)glycidonitrile; 2-[(2R,3R)-3-(4-Fluorophenyl)oxiran-2-yl]acetonitrile; (2R,3R)-rel-2-(4-Fluorophenyl)oxiranecarbonitrile; Glycidonitrile, 3-(4-fluorophenyl)-, (2R,3R)-rel-
EINECS	Contact for details

Quality Control

Every batch of Oxiranecarbonitrile, 3-(4-Fluorophenyl)-, (2R,3R)-Rel- (9Ci) is produced and tested under a strict quality management system. We employ advanced analytical techniques including chiral HPLC, GC, and NMR to ensure exceptional enantiomeric purity and chemical identity. Certificates of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles are provided with each shipment to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.