Description

4-Methoxy-3-Nitrophenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its enhanced stability and reactivity, making it a superior reagent for complex cross-coupling reactions compared to its free acid form. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as polymers for OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands for asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs serving the global life sciences market.

Basic Information

Product Name	4-Methoxy-3-Nitrophenylboronic Acid, Pinacol Ester
CAS No.	554411-20-0
Molecular Formula	C13H18BNO5
Molecular Weight	279.10 g/mol
Synonyms	4-Methoxy-3-nitrophenylboronic acid pinacol ester; 2-(4-Methoxy-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Nitro-4-methoxyphenylboronic acid pinacol ester; Pinacol (4-Methoxy-3-nitrophenyl)boronate; (4-Methoxy-3-nitrophenyl)boronic acid pinacol ester; B-(4-Methoxy-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Every batch of 4-Methoxy-3-Nitrophenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent lot-to-lot performance. Certificates of Analysis (COA) with full traceability are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.