Description

Cyclohexanamine, 4,4-Difluoro-n-Methyl- (9Ci) is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. This compound matters for its unique structural features, offering a rigid, fluorinated cyclohexyl scaffold that can impart desirable properties like metabolic stability and altered lipophilicity to target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly where a fluorinated, conformationally constrained amine moiety is required.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Material Science Research: Acts as a monomer or functionalization agent in the synthesis of fluorinated polymers and advanced materials with specific surface properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms or protein interactions due to its potential as a bioisostere.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Cyclohexanamine, 4,4-Difluoro-n-Methyl- (9Ci)
CAS No.	546093-43-0
Molecular Formula	C7H13F2N
Molecular Weight	149.18 g/mol
Synonyms	4,4-Difluoro-N-methylcyclohexanamine; N-Methyl-4,4-difluorocyclohexanamine; 4,4-Difluoro-N-methyl-cyclohexanamine; 4,4-Difluorocyclohexylmethylamine; 1-(4,4-Difluorocyclohexyl)-N-methylmethanamine; 4,4-Difluoro-N-methylcyclohexylamine; 4,4-Difluoro-N-methyl-1-cyclohexanamine
EINECS	Contact for details

Quality Control

Our Cyclohexanamine, 4,4-Difluoro-n-Methyl- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.