Description

5-(Pyrimidin-2-Yl)Thiophene-2-Carbaldehyde is a high-purity heterocyclic building block featuring a fused pyrimidine-thiophene core with an aldehyde functional group. This compound is of significant value in advanced organic synthesis, serving as a versatile precursor for constructing complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science Research: Serves as a precursor for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal-organic frameworks (MOFs) and catalytic systems.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex heterocyclic scaffolds.

Basic Information

Product Name	5-(Pyrimidin-2-Yl)Thiophene-2-Carbaldehyde
CAS No.	545424-57-5
Molecular Formula	C9H6N2OS
Molecular Weight	190.22 g/mol
Synonyms	5-(2-Pyrimidinyl)-2-thiophenecarboxaldehyde; 2-Thiophenecarboxaldehyde, 5-(2-pyrimidinyl)-; 5-(Pyrimidin-2-yl)thiophene-2-carboxaldehyde; Thiophene-2-carbaldehyde, 5-(pyrimidin-2-yl)-; 545424-57-5; 5-(2-Pyrimidyl)thiophene-2-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 5-(Pyrimidin-2-Yl)Thiophene-2-Carbaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with exacting purity standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.