Description

5-(Trifluoromethyl)-2,1,3-Benzoxadiazole is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique electronic properties imparted by the benzoxadiazole core and the trifluoromethyl group, making it a versatile intermediate for creating novel molecular architectures. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients, as well as by material scientists exploring functional dyes and electronic materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Acts as a precursor for the synthesis of organic semiconductors, fluorescent dyes, and photoactive materials for optoelectronic devices.
• Chemical Biology Probes: Employed in the design of fluorogenic tags and molecular probes for bioimaging and diagnostic assay development.
• Ligand and Catalyst Development: Utilized to construct complex chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and cyclization reactions.

Basic Information

Product Name	5-(Trifluoromethyl)-2,1,3-Benzoxadiazole
CAS No.	541539-79-1
Molecular Formula	C7H3F3N2O
Molecular Weight	188.11 g/mol
Synonyms	5-(Trifluoromethyl)benzo[c][1,2,5]oxadiazole; 5-(Trifluoromethyl)-2,1,3-benzoxadiazole; 5-Trifluoromethyl-2,1,3-benzoxadiazole; 2,1,3-Benzoxadiazole, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)benzofurazan; 5-Trifluoromethylbenzofurazan; TFM-BD; 5-CF3-Benzoxadiazole
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-2,1,3-Benzoxadiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for advanced applications and can tailor quality protocols to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.