Description

4-Bromo-2,3,6-Trifluorobenzaldehyde is a versatile fluorinated aromatic aldehyde building block, distinguished by its unique substitution pattern of bromine and fluorine atoms. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling the synthesis of advanced materials and active pharmaceutical ingredients. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated cores in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), improving electronic properties and device performance.
• Polymer Modification: Employed to introduce functional aromatic aldehydes into polymer chains, altering thermal stability and chemical resistance for high-performance plastics.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Ligand & Catalyst Development: Utilized in the preparation of specialized fluorinated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Bromo-2,3,6-Trifluorobenzaldehyde
CAS No.	537033-56-0
Molecular Formula	C7H2BrF3O
Molecular Weight	238.99 g/mol
Synonyms	2,3,6-Trifluoro-4-bromobenzaldehyde; 4-Bromo-2,3,6-trifluorobenzenecarboxaldehyde; Benzaldehyde, 4-bromo-2,3,6-trifluoro-; 4-Bromo-2,3,6-trifluoro benzaldehyde; 537033-56-0; 4-Br-2,3,6-F3-C6HCHO
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,3,6-Trifluorobenzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.