Description

2-(Trifluoromethyl)Furan-3-Carboxylic Acid is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both a furan ring and a trifluoromethyl group, makes it a critical intermediate for introducing fluorine atoms into target molecules, thereby modulating their physicochemical properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for antiviral, anti-inflammatory, and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials requiring specific fluorine content.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	2-(Trifluoromethyl)Furan-3-Carboxylic Acid
CAS No.	536718-30-6
Molecular Formula	C6H3F3O3
Molecular Weight	180.08 g/mol
Synonyms	3-Furoic acid, 2-(trifluoromethyl)-; 2-(Trifluoromethyl)-3-furancarboxylic acid; α,α,α-Trifluoro-3-furoic acid; 2-Trifluoromethylfuran-3-carboxylic acid; Furan-3-carboxylic acid, 2-(trifluoromethyl)-; 3-Carboxy-2-(trifluoromethyl)furan
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Furan-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF for moisture content, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.