Description

1H-Inden-1-Ol, 2-Ethynyl-2,3-Dihydro-, (1R,2S)-Rel- (9Ci) is a high-purity chiral intermediate of significant interest in advanced organic synthesis. Its unique indene-ol scaffold with an ethynyl substituent makes it a valuable building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical development teams for the synthesis of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Asymmetric Synthesis: Utilized as a precursor or ligand in catalytic asymmetric reactions to induce stereoselectivity.
• Material Science Research: Serves as a monomer or functional group donor in the development of novel polymers with specific optical or electronic properties.
• Agrochemical Development: Employed in the synthesis of advanced, targeted crop protection agents and plant growth regulators.
• Academic & Industrial R&D: Used in methodological studies and scale-up processes for complex organic molecule construction.

Basic Information

Product Name	1H-Inden-1-Ol, 2-Ethynyl-2,3-Dihydro-, (1R,2S)-Rel- (9Ci)
CAS No.	532957-65-6
Molecular Formula	C11H10O
Molecular Weight	158.20 g/mol
Synonyms	rel-(1R,2S)-2-Ethynyl-2,3-dihydro-1H-inden-1-ol; (1R,2S)-rel-2-Ethynylindan-1-ol; 2-Ethynyl-2,3-dihydro-1H-inden-1-ol, (1R,2S)-rel-; 532957-65-6; 2-Ethynylindan-1-ol (rel-(1R,2S)-form)
EINECS	Contact for details

Quality Control

Every batch of 1H-Inden-1-Ol, 2-Ethynyl-2,3-Dihydro-, (1R,2S)-Rel- (9Ci) is produced and tested under strict quality management protocols to ensure identity, purity, and consistency. Our standard analytical package includes HPLC for assay determination and chiral purity verification. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support custom synthesis and can tailor specifications, including enantiomeric excess (ee), to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.