Description

2,2-Difluoro-4-Iodobenzo[D][1,3]Dioxole is a high-value, multi-functional halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents on a 1,3-dioxole scaffold, makes it a versatile precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infective agents.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity-modifying effects of fluorine and iodine atoms.
• Material Science Precursor: Used in the synthesis of specialty polymers, liquid crystals, and organic electronic materials where the benzo[d][1,3]dioxole core contributes to specific optical or electronic properties.
• Cross-Coupling Reactions: The iodine atom is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira), enabling rapid diversification of the molecular scaffold.
• Fluorine Chemistry: Acts as a starting material for further fluorination or functional group manipulation studies, given the presence of reactive difluoro and iodo groups.

Basic Information

Product Name	2,2-Difluoro-4-Iodobenzo[D][1,3]Dioxole
CAS No.	531508-54-0
Molecular Formula	C7H2F2IO2
Molecular Weight	283.99 g/mol
Synonyms	4-Iodo-2,2-difluorobenzo[d][1,3]dioxole; 2,2-Difluoro-4-iodo-1,3-benzodioxole; 4-Iodo-2,2-difluoro-1,3-benzodioxole; Benzo[d][1,3]dioxole, 2,2-difluoro-4-iodo-; 2,2-Difluoro-4-iodobenzo-1,3-dioxole
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-4-Iodobenzo[D][1,3]Dioxole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.