Description

2-(4-Chlorophenyl)-5'-Fluoro-2'-Hydroxyacetophenone is a high-purity, specialized organic intermediate of significant importance in advanced chemical synthesis. Its unique molecular structure, featuring both chlorophenyl and fluorinated hydroxyacetophenone moieties, makes it a valuable building block for creating complex, bioactive molecules. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobial compounds.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging its halogenated structure for enhanced biological activity.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers and liquid crystals, where its aromatic and ketone groups contribute to material properties.
• Chemical Synthesis: Acts as a versatile synthon for constructing more complex heterocyclic compounds, such as benzofurans and chromones, in academic and industrial R&D settings.
• Analytical Reference Standard: Employed as a certified reference material (CRM) in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	2-(4-Chlorophenyl)-5'-Fluoro-2'-Hydroxyacetophenone
CAS No.	527751-48-0
Molecular Formula	C14H10ClFO2
Molecular Weight	264.68 g/mol
Synonyms	1-[5-Fluoro-2-hydroxyphenyl]-2-(4-chlorophenyl)ethanone; 2-(4-Chlorophenyl)-1-(5-fluoro-2-hydroxyphenyl)ethan-1-one; 5'-Fluoro-2'-(4-chlorophenyl)-2-hydroxyacetophenone; 2-Hydroxy-5-fluoro-2'-(4-chlorophenyl)acetophenone; 2-(p-Chlorophenyl)-1-(5-fluoro-2-hydroxyphenyl)ethanone; (5-Fluoro-2-hydroxyphenyl)(4-chlorophenyl)methanone (tautomeric form); CAS 527751-48-0
EINECS	Contact for details

Quality Control

Our production of 2-(4-Chlorophenyl)-5'-Fluoro-2'-Hydroxyacetophenone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR, NMR, and mass spectrometry, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.