Description

4-Amino-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzoic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate and versatile synthetic building block. This compound is critical for modern organic synthesis, particularly in the construction of complex molecules via Suzuki-Miyaura cross-coupling reactions. It is essential for research and development in pharmaceutical, agrochemical, and material science industries seeking to incorporate functionalized aromatic boronic ester motifs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling: Essential boronic ester reagent for forming carbon-carbon bonds in complex organic molecule assembly.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Material Science: Used in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of molecular probes.
• Academic & Industrial R&D: Fundamental reagent for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	4-Amino-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzoic Acid Methyl Ester
CAS No.	524916-42-5
Molecular Formula	C14H20BNO4
Molecular Weight	277.13 g/mol
Synonyms	Methyl 4-Amino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 3-Pinacolboryl-4-aminomethylbenzoate; 4-Amino-3-(pinacolboryl)benzoic acid methyl ester; 524916-42-5; Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-aminobenzoate; Benzoic acid, 4-amino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester
EINECS	Contact for details

Quality Control

Our 4-Amino-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.