Description

1,4-Hexadiyn-3-Ol,6-[(4R)-2,2-Diethyl-1,3-Dioxolan-4-Yl]-(9Ci) is a specialized chiral building block and advanced intermediate of significant interest in synthetic organic chemistry. Its unique molecular architecture, featuring both a diyne and a protected diol moiety, makes it a valuable precursor for constructing complex, stereodefined molecular frameworks. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for constructing specific stereocenters and carbon chains.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where its structural motifs can contribute to biological activity.
• Material Science Research: Acts as a monomer or precursor for novel polymers and functional organic materials with tailored properties.
• Academic & Industrial R&D: Employed in methodological studies and total synthesis projects to explore new chemical transformations and reaction pathways.
• Ligand and Catalyst Development: The protected diol and alkyne functionalities can be modified to create novel chiral ligands for asymmetric catalysis.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals for various technological applications.

Basic Information

Product Name	1,4-Hexadiyn-3-Ol,6-[(4R)-2,2-Diethyl-1,3-Dioxolan-4-Yl]-(9Ci)
CAS No.	521078-77-3
Molecular Formula	C13H18O3
Molecular Weight	222.28 g/mol
Synonyms	(4R)-6-(1,4-Hexadiyn-3-ol-6-yl)-2,2-diethyl-1,3-dioxolane; 6-[(4R)-2,2-Diethyl-1,3-dioxolan-4-yl]-1,4-hexadiyn-3-ol; 1,4-Hexadiyn-3-ol, 6-[(4R)-2,2-diethyl-1,3-dioxolan-4-yl]-; (R)-6-(2,2-Diethyl-1,3-dioxolan-4-yl)hexa-1,4-diyn-3-ol; Chiral Hexadiynol Dioxolane Derivative; Advanced Chiral Diol Alkyne Building Block
EINECS	Contact for details

Quality Control

Our production of 1,4-Hexadiyn-3-Ol,6-[(4R)-2,2-Diethyl-1,3-Dioxolan-4-Yl]-(9Ci) adheres to strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and oxidation; consider storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.