Description

5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-Benzofuran is a high-purity boronic ester derivative, a crucial building block in modern synthetic chemistry. Its value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for forming carbon-carbon bonds under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and functional molecule synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates, particularly those containing benzofuran scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl couplings.
• Material Science Research: Building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where precise molecular architecture is critical.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-Benzofuran
CAS No.	519054-55-8
Molecular Formula	C16H21BO3
Molecular Weight	272.15 g/mol
Synonyms	1-Benzofuran-5-boronic acid, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzofuran; 5-Benzofuranylboronic acid pinacol ester; 5-Borono-1-benzofuran pinacol ester; Benzo[b]furan-5-ylboronic acid pinacol ester; 5-(Pinacolatoboryl)benzofuran; CAS 519054-55-8.
EINECS	Contact for details

Quality Control

Every batch of 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-Benzofuran is produced and tested under a strict Quality Management System. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.