Description

1-Butanone,1-(4,5-Difluoro-2-Methylphenyl)-(9Ci) is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly within the pharmaceutical and agrochemical sectors. Industrial and research chemists need this high-purity intermediate for constructing active pharmaceutical ingredients (APIs), liquid crystal materials, and functional agrochemicals where the difluoromethylphenyl moiety is critical.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the synthesis of specialized monomers and polymers for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A valuable reagent for method development and exploring new fluorination chemistry and cross-coupling reactions in academic and industrial R&D labs.
• Fine Chemical Production: Acts as an intermediate for creating complex fragrance and flavor molecules that require specific fluorinated aromatic structures.

Basic Information

Item	Details
Product Name	1-Butanone,1-(4,5-Difluoro-2-Methylphenyl)-(9Ci)
CAS No.	519018-09-8
Molecular Formula	C11H12F2O
Molecular Weight	198.21 g/mol
Synonyms	1-(4,5-Difluoro-2-methylphenyl)butan-1-one; 4',5'-Difluoro-2'-methylbutyrophenone; 2-Methyl-4,5-difluorobutyrophenone; Butan-1-one, 1-(4,5-difluoro-2-methylphenyl)-; 519018-09-8; 4,5-Difluoro-2-methylbutyrophenone; 1-(4,5-Difluoro-o-tolyl)butan-1-one
EINECS	Contact for details

Quality Control

Our 1-Butanone,1-(4,5-Difluoro-2-Methylphenyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical data are provided with every shipment to guarantee batch-to-batch consistency and traceability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed in a dry environment to minimize moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.