Description

(4-Chloro-2,6-Difluorophenyl)Methanamine is a high-purity, halogenated benzylamine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized aromatic core with multiple points for selective chemical modification, enabling the development of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluoro and chloro substituents contribute to biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for high-performance polymers, liquid crystals, and electronic materials.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis services and contract research organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	(4-Chloro-2,6-Difluorophenyl)Methanamine
CAS No.	518357-43-2
Molecular Formula	C7H6ClF2N
Molecular Weight	177.58 g/mol
Synonyms	1-(4-Chloro-2,6-difluorophenyl)methanamine; (4-Chloro-2,6-difluorobenzyl)amine; 4-Chloro-2,6-difluorobenzylamine; α-Amino-4-chloro-2,6-difluorotoluene; 4-Chloro-2,6-difluoro-benzenemethanamine; Benzenemethanamine, 4-chloro-2,6-difluoro-
EINECS	Contact for details

Quality Control

Our (4-Chloro-2,6-Difluorophenyl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.