Description

2-[(3-Chlorophenyl)Methyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 517920-59-1 is a high-purity organoboron reagent, specifically a pinacol boronic ester derivative, essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient and selective formation of carbon-carbon bonds. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and other complex aromatic structures central to drug discovery and material science.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing chlorinated phenyl motifs.
• Agrochemical Product Development: Employed in creating novel herbicides, fungicides, and insecticides with targeted activity.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands and organometallic catalysts.
• Polymer and Material Science: Incorporated into the synthesis of advanced polymers, OLED materials, and other functional organic materials.
• Chemical Biology and Medicinal Chemistry: Utilized for the site-specific modification of biomolecules and in structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-[(3-Chlorophenyl)Methyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	517920-59-1
Molecular Formula	C13H18BClO2
Molecular Weight	252.54 g/mol
Synonyms	(3-Chlorobenzyl)boronic acid pinacol ester; 1-[(3-Chlorophenyl)methyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Chlorobenzylboronic Acid Pinacol Ester; (3-Chlorobenzyl)BPin; 2-(3-Chlorobenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (3-Chlorobenzyl)boronate
EINECS	Contact for details

Quality Control

Our 2-[(3-Chlorophenyl)Methyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.