Description

3-((4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Methyl)Benzonitrile is a high-value, synthetically versatile boronic ester derivative, serving as a critical building block in modern organic synthesis. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in constructing complex molecules for next-generation herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Research & Development: An indispensable reagent in medicinal chemistry and process chemistry for lead optimization and scalable route development.
• Ligand and Catalyst Preparation: Employed in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric synthesis.
• Life Sciences: Utilized in the preparation of bioconjugates and molecular probes for diagnostic and imaging applications.

Basic Information

Product Name	3-((4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Methyl)Benzonitrile
CAS No.	517920-57-9
Molecular Formula	C14H18BNO2
Molecular Weight	243.11 g/mol
Synonyms	(3-Cyanophenylmethyl)boronic acid pinacol ester; 3-(Pinacolatoborylmethyl)benzonitrile; (3-Cyanobenzyl)boronic acid pinacol ester; 3-((4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)benzonitrile; Benzonitrile, 3-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]-; 3-Cyanobenzylboronic Acid Pinacol Ester; Pinacol (3-Cyanobenzyl)boronate
EINECS	Contact for details

Quality Control

Every batch of 3-((4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Methyl)Benzonitrile is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity, identity, and consistency. Our standard quality commitment includes comprehensive analysis via HPLC, NMR, and GC-MS. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.