Description

5-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol is a versatile and high-value organoboron intermediate, specifically a protected boronic acid derivative. This compound is critical for enabling precise carbon-carbon bond formation in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecular architectures, such as active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for creating organic electronic materials and functional polymers.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and bioconjugation tools.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic synthesis and catalysis studies.
• Liquid Crystal & OLED Material Development: Used as a synthon for constructing complex aromatic cores in advanced display materials.

Basic Information

Product Name	5-Methyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol
CAS No.	517864-13-0
Molecular Formula	C₁₃H₁₉BO₃
Molecular Weight	234.10 g/mol
Synonyms	2-Hydroxy-5-methylphenylboronic acid pinacol ester; 5-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; (5-Methyl-2-hydroxyphenyl)boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-methylphenol; 5-Methylsalicylaldehyde pinacol boronate; 5-Methyl-2-hydroxybenzeneboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.