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2-(2-(Methoxymethoxy)-4-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 517864-11-8


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CAS No.:517864-11-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(2-(Methoxymethoxy)-4-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS research.
  • Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides requiring specific aryl-aryl couplings.
  • Material Science: Enables the creation of organic electronic materials, such as polymers for OLEDs and organic photovoltaics, through controlled polymerization.
  • Chemical Research & Development: A versatile reagent for academic and industrial research in palladium-catalyzed cross-coupling reactions.
  • Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts.
  • Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name 2-(2-(Methoxymethoxy)-4-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No. 517864-11-8
Molecular Formula C15H23BO4
Molecular Weight 278.15 g/mol
Synonyms 4-Methyl-2-(methoxymethoxy)phenylboronic acid pinacol ester; 2-(2-(Methoxymethoxy)-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-(Methoxymethoxy)-4-methylphenyl)boronic acid pinacol ester; MOM-Protected 4-Methylphenylboronic Acid Pinacol Ester; 517864-11-8; 4-Methyl-2-(MOM-oxy)phenylboronic acid pinacol ester; Pinacol [2-(methoxymethoxy)-4-methylphenyl]boronate
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Quality Control

Our 2-(2-(Methoxymethoxy)-4-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive coupling reactions. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliance for advanced intermediates and adhere to relevant REACH regulations for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and reactivity.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥97.0% (Area %)
Purity (NMR) ≥95.0%
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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