Description

L-Ribo-Hexonic Acid, 2,4-Dideoxy-4-Methyl-, δ-Lactone (9Ci) is a specialized chiral building block and sugar derivative of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals, particularly nucleoside analogs and carbohydrate-based therapeutics. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex bioactive molecules. The compound, identified by CAS No. 515868-99-2, offers a precise stereochemical framework for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of nucleoside analogs and antiviral/anticancer drug candidates.
• Medicinal Chemistry Research: Used as a building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Carbohydrate Chemistry: Acts as a starting material or intermediate for the synthesis of complex sugars, glycoconjugates, and glycomimetics.
• Process Development & Scale-up: Employed in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Biochemical Research: Potential use in studying enzyme mechanisms or as a substrate analog for glycosidases and other carbohydrate-processing enzymes.
• Fine Chemical Synthesis: Utilized in the preparation of specialty chemicals, chiral ligands, and catalysts for asymmetric synthesis.

Basic Information

Product Name	L-Ribo-Hexonic Acid, 2,4-Dideoxy-4-Methyl-, δ-Lactone (9Ci)
CAS No.	515868-99-2
Molecular Formula	C7H12O4
Molecular Weight	160.17 g/mol
Synonyms	2,4-Dideoxy-4-methyl-L-ribo-hexonic acid, δ-lactone; (3R,5R)-5-(Hydroxymethyl)-3-methyloxolan-2-one; 4-Methyl-2,4-dideoxy-L-ribo-hexono-1,5-lactone; L-2,4-Dideoxy-4-methylribo-hexonic acid 1,5-lactone; 4-Methyl-2,4-dideoxy-L-ribo-hexonolactone; A chiral sugar lactone intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our L-Ribo-Hexonic Acid, 2,4-Dideoxy-4-Methyl-, δ-Lactone (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure compliance with research and development standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.