Description

Benzamide, n-Cyclopropyl-4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, multi-functional organic building block featuring a benzamide core integrated with a cyclopropyl group and a pinacol boronate ester. This compound matters for its dual functionality, serving as a versatile intermediate in modern synthetic chemistry, particularly in cross-coupling reactions like the Suzuki-Miyaura coupling. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise molecular scaffolds for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as OLEDs and semiconductors, due to its conjugated system and boronic ester handle.
• Suzuki-Miyaura Cross-Coupling: The pinacol boronate ester group makes it an ideal partner for palladium-catalyzed coupling with aryl halides, enabling efficient carbon-carbon bond formation.
• Chemical Biology & Proteomics: Utilized in the development of chemical probes and affinity tags for studying protein function and interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences industry with complex, bespoke organic molecules.

Basic Information

Product Name	Benzamide, n-Cyclopropyl-4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	515135-67-8
Molecular Formula	C₁₇H₂₄BNO₃
Molecular Weight	301.19 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-cyclopropyl-4-methylbenzamide; N-Cyclopropyl-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 4-Methyl-3-(pinacolboryl)-N-cyclopropylbenzamide; 3-Boronic acid, 4-methyl-N-cyclopropylbenzamide, pinacol ester; Benzamide, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-cyclopropyl-4-methyl-; CAS 515135-67-8
EINECS	Contact for details

Quality Control

Every batch of Benzamide, n-Cyclopropyl-4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and LC-MS is supplied with each shipment, ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed under an inert atmosphere to prevent moisture absorption and degradation of the boronate ester functionality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.