Description

(2E)-3-(Dimethylamino)-1-[3-(Trifluoromethyl)Phenyl]Prop-2-En-1-One is a specialized organic compound featuring a trifluoromethylphenyl group and a dimethylamino-substituted enone moiety. This structure is of significant interest in advanced organic synthesis, particularly for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammation.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides and fungicides, leveraging the bioactivity of the trifluoromethyl group.
• Material Science Research: Used in the synthesis of organic semiconductors and photoactive materials for electronic applications.
• Chemical Biology Probes: Acts as a scaffold for creating fluorescent tags or enzyme inhibitors used in biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	(2E)-3-(Dimethylamino)-1-[3-(Trifluoromethyl)Phenyl]Prop-2-En-1-One
CAS No.	511244-84-1
Molecular Formula	C12H12F3NO
Molecular Weight	243.23 g/mol
Synonyms	3-(Dimethylamino)-1-[3-(trifluoromethyl)phenyl]-2-propen-1-one; (E)-3-(Dimethylamino)-1-(3-(trifluoromethyl)phenyl)prop-2-en-1-one; 1-[3-(Trifluoromethyl)phenyl]-3-(dimethylamino)-2-propen-1-one; 3-(Dimethylamino)-1-(3-trifluoromethylphenyl)-2-propen-1-one; (E)-3-(Dimethylamino)-1-(3-trifluoromethylphenyl)prop-2-en-1-one; DMAPTF; 511244-84-1
EINECS	Contact for details

Quality Control

Our (2E)-3-(Dimethylamino)-1-[3-(Trifluoromethyl)Phenyl]Prop-2-En-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality ensures reliable performance in your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.