Description

4-(2,6-Difluorophenyl)-1,3-Thiazol-2-Amine is a high-purity, advanced pharmaceutical intermediate featuring a difluorophenyl-substituted thiazole core. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific fluorine substitution for enhanced metabolic stability and bioavailability. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and anti-infective therapeutic classes.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides and fungicides, leveraging the biological activity of the thiazole ring.
• Chemical Research & Development: Used in academic and industrial R&D for exploring novel heterocyclic compounds and fluorine chemistry.
• Material Science Precursor: Potential application in the synthesis of specialty chemicals and functional materials, such as organic semiconductors or ligands for catalysis.

Basic Information

Product Name	4-(2,6-Difluorophenyl)-1,3-Thiazol-2-Amine
CAS No.	510738-34-8
Molecular Formula	C9H6F2N2S
Molecular Weight	212.22 g/mol
Synonyms	2-Amino-4-(2,6-difluorophenyl)thiazole; 4-(2,6-Difluorophenyl)-2-aminothiazole; 2-Thiazolamine, 4-(2,6-difluorophenyl)-; 510738-34-8; 4-(2,6-Difluorophenyl)thiazol-2-amine
EINECS	Contact for details

Quality Control

Our 4-(2,6-Difluorophenyl)-1,3-Thiazol-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.