Description

Cyclopropanemethanol, 2,2-Difluoro-α-Methyl-, Acetate (9Ci) is a specialized fluorinated cyclopropane derivative, a high-value intermediate prized for its unique structural motif. This compound is critical for introducing the sterically constrained and electronically modified cyclopropane ring into target molecules, enabling fine-tuning of biological activity and physical properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, antiviral agents, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorinated cyclopropane moiety can enhance metabolic stability, bioavailability, and target specificity.
• Material Science Research: Serves as a precursor for specialty monomers or ligands in the development of advanced polymers, liquid crystals, or functional materials with tailored properties.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags to study biological processes and protein interactions due to its potential for bioorthogonal reactivity.
• Catalyst & Ligand Development: Acts as a scaffold for designing novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	Cyclopropanemethanol, 2,2-Difluoro-α-Methyl-, Acetate (9Ci)
CAS No.	509072-71-3
Molecular Formula	C7H10F2O2
Molecular Weight	164.15 g/mol
Synonyms	2,2-Difluoro-α-methylcyclopropanemethanol acetate; Acetic acid 2,2-difluoro-1-methylcyclopropylmethyl ester; 1-Methyl-2,2-difluorocyclopropanemethyl acetate; (1-Methyl-2,2-difluorocyclopropyl)methyl acetate; 2,2-Difluoro-1-methylcyclopropylmethyl acetate; Cyclopropanemethanol, 2,2-difluoro-α-methyl-, acetate
EINECS	Contact for details

Quality Control

Our Cyclopropanemethanol, 2,2-Difluoro-α-Methyl-, Acetate (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 95.0% (Research Grade)
Purity (by GC/HPLC)	≥ 98.0% (Premium Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.