Description

1(2H)-Naphthalenone, 2-Fluoro-3,4-Dihydro-5-Hydroxy- is a specialized fluorinated naphthalenone derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in its unique molecular scaffold, which combines a fluorinated, dihydro-naphthalenone structure with a phenolic hydroxyl group, enabling precise modifications in complex synthesis pathways. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in fluorinated compound libraries for medicinal chemistry research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Organic Synthesis: A versatile precursor for constructing complex polycyclic structures and heterocycles in academic and industrial R&D settings.
• Material Science: Potential intermediate in the synthesis of specialty polymers and advanced organic electronic materials.
• Fluorine Chemistry Studies: Serves as a model compound for studying the effects of fluorine substitution on the reactivity and properties of aromatic ketones.

Basic Information

Product Name	1(2H)-Naphthalenone, 2-Fluoro-3,4-Dihydro-5-Hydroxy-
CAS No.	507477-10-3
Molecular Formula	C₁₀H₇FO₂
Molecular Weight	178.16 g/mol
Synonyms	2-Fluoro-5-hydroxy-3,4-dihydronaphthalen-1(2H)-one; 5-Hydroxy-2-fluoro-1,2,3,4-tetrahydronaphthalen-1-one; 2-Fluoro-3,4-dihydro-5-hydroxy-1(2H)-naphthalenone; 2-Fluoro-5-hydroxy-α-tetralone; Fluorinated hydroxy-tetralone; 507477-10-3; FC-507477-10-3
EINECS	Contact for details

Quality Control

Our production of 1(2H)-Naphthalenone, 2-Fluoro-3,4-Dihydro-5-Hydroxy- adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to strong alkalis and fluorides, keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.