Description

3,5-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is a high-value, multi-functional boronic ester derivative of a substituted phenol. This compound matters as a critical advanced pharmaceutical intermediate and versatile organic synthesis building block, enabling the construction of complex molecules through efficient cross-coupling reactions. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boron-containing reagent for constructing biaryl and heterobiaryl structures prevalent in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides requiring specific phenolic and boronic ester functionalities.
• Liquid Crystal & OLED Material Precursor: Used in the development of organic electronic materials and advanced display technologies.
• Polymer Modification: Incorporation into polymer backbones or as an end-group for creating functional materials with tailored properties.
• Chemical Biology & Proteomics: Serves as a probe or linker in the development of biochemical tools and targeted therapies.

Basic Information

Product Name	3,5-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol
CAS No.	507462-90-0
Molecular Formula	C14H21BO3
Molecular Weight	248.13 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,5-dimethylphenol; 2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; 3,5-Dimethyl-4-(pinacolatoboryl)phenol; Phenol, 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 507462-90-0; Boronic acid, B-(4-hydroxy-2,6-dimethylphenyl)-, pinacol ester
EINECS	Contact for details

Quality Control

Our 3,5-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.