Description

2-Propen-1-One, 1-(2-Chlorophenyl)-2-Fluoro- (9Ci) is a specialized fluorinated and chlorinated α,β-unsaturated ketone building block. This compound is valued for its unique molecular architecture, which makes it a critical intermediate in advanced organic synthesis, particularly for constructing complex heterocyclic systems. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the fluorine and chlorine substituents enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic electronic materials due to its conjugated system.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and inhibitors for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses serving the life sciences sector.

Basic Information

Item	Detail
Product Name	2-Propen-1-One, 1-(2-Chlorophenyl)-2-Fluoro- (9Ci)
CAS No.	506437-48-5
Molecular Formula	C9H6ClFO
Molecular Weight	184.59 g/mol
Synonyms	1-(2-Chlorophenyl)-2-fluoroprop-2-en-1-one; 2-Chloro-α-fluorocinnamaldehyde; 2'-Chloro-2-fluorochalcone; (2-Chlorophenyl)(fluoro)ethenone; 2-Fluoro-1-(2-chlorophenyl)prop-2-en-1-one; α-Fluoro-2'-chlorochalcone; 506437-48-5
EINECS	Contact for details

Quality Control

Every batch of 2-Propen-1-One, 1-(2-Chlorophenyl)-2-Fluoro- (9Ci) is produced and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC-MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.