Description

3,4,5-Trifluoro-Benzamidine is a high-purity, fluorinated benzamidine derivative, a critical building block in modern organic synthesis. Its value lies in its role as a key precursor for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials who require reliable, high-quality intermediates. The product is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and meets the stringent requirements of industrial-scale production.

Application

• Pharmaceutical Intermediate: A vital precursor in the synthesis of novel drug candidates, particularly protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the stability imparted by the trifluoro substitution.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry and material science for creating complex fluorinated aromatic structures.
• Ligand and Catalyst Preparation: Employed in the preparation of specialized ligands for metal catalysis and molecular recognition applications.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value fine chemicals and specialty performance materials.

Basic Information

Product Name	3,4,5-Trifluoro-Benzamidine
CAS No.	504404-35-7
Molecular Formula	C7H5F3N2
Molecular Weight	174.12 g/mol
Synonyms	3,4,5-Trifluorobenzamidine; Benzenecarboximidamide, 3,4,5-trifluoro-; 3,4,5-Trifluorobenzenecarboximidamide; 3,4,5-Trifluorobenzene-1-carboximidamide; 3,4,5-Trifluoro-benzamidine hydrochloride (salt form common); 3,4,5-Trifluoro-benzenecarboximidamide; Amidino-3,4,5-trifluorobenzene
EINECS	Contact for details

Quality Control

Our 3,4,5-Trifluoro-Benzamidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.