Description

2-(Trimethylsilyl)Acetylene-1-Boronic Acid Diisopropyl Ester is a highly versatile and valuable organoboron building block used in advanced organic synthesis. Its core value lies in enabling efficient carbon-carbon bond formation, particularly in the synthesis of complex molecules and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-purity intermediates for cross-coupling reactions.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and conjugated systems in drug discovery and material synthesis.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and complex molecular scaffolds.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science & OLED Development: Serves as a precursor for organic light-emitting diodes (OLEDs) and other electronic materials.
• Polymer Chemistry: Used to introduce acetylene and silyl-protected functional groups into polymer backbones.
• Academic & Process R&D: A critical tool for methodology development and exploring new synthetic pathways in research laboratories.

Basic Information

Product Name	2-(Trimethylsilyl)Acetylene-1-Boronic Acid Diisopropyl Ester
CAS No.	503565-80-8
Molecular Formula	C11H23BO2Si
Molecular Weight	226.20 g/mol
Synonyms	2-(Trimethylsilyl)ethynylboronic Acid Diisopropyl Ester; (2-(Trimethylsilyl)ethynyl)boronic Acid Diisopropyl Ester; Diisopropyl 2-(Trimethylsilyl)ethynylboronate; (Trimethylsilyl)acetylene Boronic Acid Diisopropyl Ester; TMS-Acetylene Boronic Ester; 503565-80-8; Boronic acid, B-[2-(trimethylsilyl)ethynyl]-, di-1-methylethyl ester
EINECS	Contact for details

Quality Control

Our 2-(Trimethylsilyl)Acetylene-1-Boronic Acid Diisopropyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and consistency for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, and well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air, moisture, or light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.