Description

8-Oxabicyclo[3.2.1]Oct-6-Ene-2-Acetaldehyde,1,5-Diethyl-3-Oxo-,(1R,2S,5R)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic oxabicyclo compound, serving as a sophisticated chiral building block and synthetic intermediate. Its complex, rigid molecular framework makes it a valuable precursor for the synthesis of biologically active molecules and fine chemicals, where precise stereochemistry is critical. This compound is primarily targeted at research and development laboratories in the pharmaceutical, agrochemical, and advanced material science sectors, where it is used to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) or anti-infective agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its bicyclic structure can contribute to unique modes of action and selectivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands used in asymmetric hydrogenation and other catalytic transformations.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, fragrances, and other high-value specialty chemicals.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties due to its strained ring system.
• Academic & Contract Research: A valuable tool for methodology development in organic synthesis and stereochemistry studies within university and CRO laboratories.

Basic Information

Product Name	8-Oxabicyclo[3.2.1]Oct-6-Ene-2-Acetaldehyde,1,5-Diethyl-3-Oxo-,(1R,2S,5R)-Rel-(9Ci)
CAS No.	503142-85-6
Molecular Formula	C13H18O3
Molecular Weight	222.28 g/mol
Synonyms	(1R,2S,5R)-rel-1,5-Diethyl-3-oxo-8-oxabicyclo[3.2.1]oct-6-ene-2-acetaldehyde; 8-Oxabicyclo[3.2.1]oct-6-ene-2-acetaldehyde, 1,5-diethyl-3-oxo-, (1R,2S,5R)-rel-; Bicyclic Oxabicyclo Aldehyde Derivative; 1,5-Diethyl-3-oxo-8-oxabicyclo[3.2.1]oct-6-ene-2-acetaldehyde (rel); Chiral Bicyclic Keto-Aldehyde Intermediate
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict quality protocols to ensure high chemical purity and stereochemical integrity. Our quality control includes comprehensive analytical techniques such as HPLC, GC, NMR, and chiral analysis to verify identity, purity, and enantiomeric/excess. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications. We adhere to cGMP principles where applicable to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.