Description

cis-5-Norbornene-Endo-2,3-Dicarboxylic Acid is a high-purity, functionalized norbornene derivative characterized by its rigid bicyclic structure and two carboxylic acid groups in a specific stereochemical configuration. This compound is a versatile and critical building block in advanced organic synthesis, particularly valued for its role in creating polymers with tailored properties and complex pharmaceutical intermediates. It is essential for R&D chemists and process engineers in the pharmaceutical, specialty polymer, and advanced materials sectors who require precise molecular architecture for developing new products.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a rigid, bicyclic scaffold.
• Specialty Polymer Monomer: Used in the production of addition-polymerization polynorbornenes, ROMP (Ring-Opening Metathesis Polymerization) polymers, and other high-performance resins for electronics and optics.
• Crosslinking Agent: Functions as a diacid crosslinker in epoxy, polyester, or other thermoset resin formulations to enhance thermal stability and mechanical strength.
• Ligand Synthesis: Employed in the preparation of complex chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Organic Synthesis Building Block: Utilized in Diels-Alder reactions and other cycloadditions to construct complex polycyclic structures in medicinal and process chemistry.
• Analytical Reference Standard: Provides a certified standard for quality control and analytical method development in chemical manufacturing.

Basic Information

Product Name	cis-5-Norbornene-Endo-2,3-Dicarboxylic Acid
CAS No.	3853-88-1
Molecular Formula	C9H10O4
Molecular Weight	182.17 g/mol
Synonyms	5-Norbornene-2,3-dicarboxylic acid, endo-; endo-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid; endo-cis-5-Norbornene-2,3-dicarboxylic acid; 3a,4,7,7a-Tetrahydro-4,7-methanoisobenzofuran-1,3-dione, dihydro-; NSC 52406; endo-Nadicanhydride (hydrolyzed); Bicyclo[2.2.1]hept-5-ene-endo-2,3-dicarboxylic acid
EINECS	223-363-3

Quality Control

Our cis-5-Norbornene-Endo-2,3-Dicarboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for all shipments upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, ensure containers are made of compatible materials (e.g., glass, PTFE).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	168 - 172 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.