Description

3-(Chloroacetyl)-3-Azabicyclo[3.2.2]Nonane is a specialized bicyclic organic compound featuring a chloroacetyl functional group, serving as a key chiral intermediate and building block in advanced organic synthesis. Its unique bridged-ring structure and reactive carbonyl chloride moiety make it invaluable for constructing complex molecular architectures with high stereochemical control. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and sophisticated fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its bicyclic scaffold for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.
• Material Science Research: Potential building block for polymers and advanced materials with tailored properties.

Basic Information

Product Name	3-(Chloroacetyl)-3-Azabicyclo[3.2.2]Nonane
CAS No.	1132-20-3
Molecular Formula	C10H16ClNO
Molecular Weight	201.69 g/mol
Synonyms	3-Azabicyclo[3.2.2]nonane, 3-(chloroacetyl)-; 3-(Chloroacetyl)-3-azabicyclo[3.2.2]nonane; 3-Chloroacetyl-3-azabicyclo[3.2.2]nonane; 1-(3-Azabicyclo[3.2.2]non-3-yl)-2-chloroethanone; 3-Azabicyclo[3.2.2]nonan-3-yl chloro ketone; 3-(Chloroacetyl)quinuclidine (structural analog); Bicyclo[3.2.2]nonan-3-amine, N-(chloroacetyl)-
EINECS	Contact for details

Quality Control

Our 3-(Chloroacetyl)-3-Azabicyclo[3.2.2]Nonane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.