Description

6-Oxo-6-(4-Trifluoromethylphenyl)Hexanoic Acid is a high-value, fluorinated organic building block characterized by its ketone and carboxylic acid functional groups. This compound is essential for research and development in advanced organic synthesis, particularly for introducing the bioisosteric and lipophilic trifluoromethylphenyl moiety into target molecules. It is primarily sought by pharmaceutical, agrochemical, and advanced material chemists for the creation of novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Advanced Polymer Modification: Incorporated into polymer chains to alter physical properties such as thermal stability, chemical resistance, and refractive index.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in medicinal chemistry and material science.
• Custom Synthesis Service: Provided as a substrate for contract research organizations (CROs) and CDMOs for client-specific molecule development.

Basic Information

Product Name	6-Oxo-6-(4-Trifluoromethylphenyl)Hexanoic Acid
CAS No.	502651-38-9
Molecular Formula	C₁₃H₁₃F₃O₃
Molecular Weight	274.24 g/mol
Synonyms	6-Oxo-6-[4-(trifluoromethyl)phenyl]hexanoic acid; 6-Oxo-6-(4-trifluoromethylphenyl)caproic acid; 4-(Trifluoromethyl)benzoylbutyric acid; ω-Oxo-4-(trifluoromethyl)benzenepentanoic acid; 5-(4-Trifluoromethylbenzoyl)valeric acid; 6-(4-Trifluoromethylphenyl)-6-oxohexanoic acid; 4'-Trifluoromethyl-δ-oxobenzenevaleric acid
EINECS	Contact for details

Quality Control

Our 6-Oxo-6-(4-Trifluoromethylphenyl)Hexanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets rigorous R&D and pilot-scale production requirements. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.