Description

1-Methoxyiminoindan-5-Boronic Acid is a specialized organoboron building block of significant importance in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecular architectures through cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing indan or related heterocyclic scaffolds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by facilitating the introduction of the boronic acid moiety into complex molecules.
• Material Science: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological processes and target engagement.
• Catalyst Ligand Synthesis: Utilized for constructing sophisticated ligand frameworks for transition metal catalysts used in asymmetric synthesis.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	1-Methoxyiminoindan-5-Boronic Acid
CAS No.	502498-89-7
Molecular Formula	C₁₀H₁₂BNO₃
Molecular Weight	205.02 g/mol
Synonyms	5-Borono-1-methoxyiminoindane; 1-(Methoxyimino)-1H-indene-5-boronic Acid; (1-Methoxyimino-2,3-dihydro-1H-inden-5-yl)boronic Acid; 1-Methoxyiminoindan-5-ylboronic Acid; 1H-Indene-5-boronic acid, 1-(methoxyimino)-; 502498-89-7; B-1-Methoxyiminoindan-5-ylboronic Acid
EINECS	Contact for details

Quality Control

Our 1-Methoxyiminoindan-5-Boronic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive cross-coupling reactions. Each lot undergoes comprehensive analysis including HPLC for purity, NMR for structural confirmation, and boron content analysis. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the product should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For long-term stability, storage at 2-8°C is recommended. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Boron Content	Conforms to theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.