Description

2-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Oxazole is a high-value, functionalized heterocyclic boronic ester derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing novel active compounds.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate: Used in the research and development of new drug candidates, particularly those containing oxazole and biphenyl motifs.
• Agrochemical Synthesis: Serves as a building block for creating novel pesticides and herbicides with enhanced efficacy.
• Materials Science & OLED Development: A precursor for synthesizing organic electronic materials, including ligands for metal complexes and emissive layers.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and sensors for biological imaging and diagnostic applications.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening in medicinal chemistry.

Basic Information

Product Name	2-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Oxazole
CAS No.	501944-79-2
Molecular Formula	C15H18BNO3
Molecular Weight	271.12 g/mol
Synonyms	4-(Oxazol-2-yl)phenylboronic acid pinacol ester; 2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]oxazole; 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)oxazole; 4-(2-Oxazolyl)benzeneboronic Acid Pinacol Ester; 2-(4-Pinacolatoboronphenyl)oxazole; 501944-79-2; Oxazole Boronic Ester PIN; 2-(4-Boronophenyl)oxazole pinacol ester
EINECS	Contact for details

Quality Control

Our 2-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Oxazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.