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4-(4-Methylthiophenyl)Phenylboronic Acid CAS NO 501944-48-5


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CAS No.:501944-48-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-(4-Methylthiophenyl)Phenylboronic Acid is a high-purity organoboron compound, serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This boronic acid is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors, where it is used to develop active pharmaceutical ingredients (APIs) and organic electronic components.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those containing biphenyl or heterobiaryl motifs for therapeutic applications.
  • Suzuki-Miyaura Cross-Coupling Reactions: Serves as a reliable boronic acid reagent for forming carbon-carbon bonds between aromatic rings, a fundamental transformation in medicinal and process chemistry.
  • Material Science Research: Used in the development of organic light-emitting diodes (OLEDs), liquid crystals, and other functional organic materials requiring specific aryl-aryl linkages.
  • Agrochemical Synthesis: Employed in the research and production of advanced crop protection agents and herbicides.
  • Chemical Biology & Probe Development: Utilized for creating molecular probes and sensors that leverage boronic acid's affinity for diols and other biological targets.

Basic Information

Product Name 4-(4-Methylthiophenyl)Phenylboronic Acid
CAS No. 501944-48-5
Molecular Formula C13H13BO2S
Molecular Weight 244.12 g/mol
Synonyms [4-(4-Methylthiophenyl)phenyl]boronic acid; 4'-(Methylthio)[1,1'-biphenyl]-4-boronic acid; (4'-Methylthio[1,1'-biphenyl]-4-yl)boronic acid; 4-(4-Methylsulfanylphenyl)benzeneboronic acid; B-[4-(4-Methylthiophenyl)phenyl]boronic acid; 4-(p-Methylthiophenyl)phenylboronic Acid
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Quality Control

Our 4-(4-Methylthiophenyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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