Description

5-Fluorobenzothiophene-2-Boronic Acid is a high-purity boronic acid derivative and a key synthetic building block in modern organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a building block for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new catalytic processes and complex molecule synthesis.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: Used in the design and synthesis of molecular probes for bioimaging and diagnostic applications.

Basic Information

Product Name	5-Fluorobenzothiophene-2-Boronic Acid
CAS No.	501944-42-9
Molecular Formula	C8H6BFO2S
Molecular Weight	195.01 g/mol
Synonyms	(5-Fluorobenzo[b]thiophen-2-yl)boronic acid; 2-Borono-5-fluorobenzo[b]thiophene; 5-Fluoro-2-benzothienylboronic acid; 5-Fluoro-1-benzothiophene-2-boronic acid; 5-Fluorobenzo[b]thiophene-2-boronic acid pinacol ester (protected form); 5-F-BT-2-BA; 5-F-2-BTBA
EINECS	Contact for details

Quality Control

Our 5-Fluorobenzothiophene-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.