Description

2,3-Difluoro-1,4-Diiodobenzene is a highly functionalized halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its unique combination of fluorine and iodine substituents makes it a versatile precursor for constructing complex molecules, particularly in the development of pharmaceuticals and agrochemicals. This compound is essential for researchers and manufacturers in the fine chemical, pharmaceutical, and materials science industries who require precise, high-purity intermediates for cross-coupling reactions and other transformative chemical processes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring a difluorinated aromatic core.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science: Building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its halogenated structure.
• Cross-Coupling Reactions: Serves as an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings, leveraging the reactive iodine atoms.
• Ligand and Catalyst Development: Used to synthesize complex chelating ligands and organocatalysts for asymmetric synthesis.
• Research & Development: A valuable tool for medicinal chemistry and chemical biology research in exploring new chemical entities and structure-activity relationships.

Basic Information

Product Name	2,3-Difluoro-1,4-Diiodobenzene
CAS No.	501433-06-3
Molecular Formula	C6H2F2I2
Molecular Weight	377.88 g/mol
Synonyms	1,4-Diiodo-2,3-difluorobenzene; Benzene, 1,4-diiodo-2,3-difluoro-; 2,3-Difluoro-p-diiodobenzene; 2,3-Difluoro-1,4-diiodo-benzene; 1,4-Diiodo-2,3-difluoro-benzene; 2,3-Difluoro-1,4-diiodobenzol; p-Diiodo-2,3-difluorobenzene
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-1,4-Diiodobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.