Description

2-Fluoro-1,3-diiodobenzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, offers versatile reactivity for selective cross-coupling and functionalization reactions. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries to develop novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging the fluorine atom for metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the diiodo-fluoroarene scaffold introduces specific biological activity.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of fluorinated liquid crystals, organic semiconductors, and polymers with tailored electronic and optical properties.
• Cross-Coupling Reactions: The iodine atoms are excellent substrates for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings, enabling rapid diversification of the benzene core.
• Fluorine Chemistry Studies: Acts as a model compound for studying the electronic effects and reactivity patterns of fluoro- and iodo-substituted arenes.

Basic Information

Product Name	2-Fluoro-1,3-Diiodobenzene
CAS No.	501433-04-1
Molecular Formula	C6H3FI2
Molecular Weight	347.89 g/mol
Synonyms	1,3-Diiodo-2-fluorobenzene; 2-Fluorobenzene-1,3-diyl diiodide; 2-Fluorom-phenylene diiodide; 2-Fluoro-1,3-diiodo-benzene; Benzene, 2-fluoro-1,3-diiodo-; 2-Fluororesorcinol diiodide; m-Diiodo-2-fluorobenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-1,3-Diiodobenzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA), including purity assay and impurity profile, is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.