Description

Ethanone, 2-Fluoro-1-(3-Fluoro-4-Methoxyphenyl)- (9Ci) is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific fluorine substitution pattern is crucial for modulating biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorinated motifs into complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where fluorine atoms enhance lipophilicity and environmental stability.
• Liquid Crystal Materials: Acts as a precursor for fluorinated mesogens used in advanced display technologies.
• Organic Electronic Materials: Employed in the synthesis of fluorinated organic semiconductors and charge-transport materials.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and structure-activity relationship (SAR) studies due to its defined fluorination pattern.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke fluorinated compounds under cGMP or research-grade conditions.

Basic Information

Product Name	Ethanone, 2-Fluoro-1-(3-Fluoro-4-Methoxyphenyl)- (9Ci)
CAS No.	501426-62-6
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	2-Fluoro-1-(3-fluoro-4-methoxyphenyl)ethanone; 1-(3-Fluoro-4-methoxyphenyl)-2-fluoroethanone; 3-Fluoro-4-methoxy-α-fluoroacetophenone; α,3-Difluoro-4-methoxyacetophenone; 2-Fluoro-1-(3-fluoro-4-methoxyphenyl)ethan-1-one; CAS 501426-62-6
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Fluoro-1-(3-Fluoro-4-Methoxyphenyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. For advanced applications, we offer material produced under cGMP guidelines and can support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0% (Standard Grade)
Purity (HPLC)	≥99.0% (High Purity Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.