Description

4-(4-Boc-Piperazino-1-Yl)-3-Fluorobenzaldehyde is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine moiety and a reactive aldehyde group. This compound is critically important for the synthesis of complex bioactive molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions and pharmaceutical companies engaged in developing novel therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of targeted drug candidates, especially in oncology and CNS research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile reactive sites.
• Protease & Kinase Inhibitor Development: Serves as a core scaffold for constructing molecules designed to inhibit specific enzymes.
• Chemical Biology: Employed in the development of molecular probes and tools for studying biological pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Academic Research: Used in university laboratories for pioneering research in organic synthesis and drug design methodologies.

Basic Information

Product Name	4-(4-Boc-Piperazino-1-Yl)-3-Fluorobenzaldehyde
CAS No.	501126-37-0
Molecular Formula	C16H21FN2O3
Molecular Weight	308.35 g/mol
Synonyms	3-Fluoro-4-(4-(tert-butoxycarbonyl)piperazin-1-yl)benzaldehyde; 4-(N-Boc-piperazinyl)-3-fluorobenzaldehyde; 1-Boc-4-(4-formyl-2-fluorophenyl)piperazine; tert-Butyl 4-(4-formyl-2-fluorophenyl)piperazine-1-carboxylate; 4-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-3-fluorobenzaldehyde; 501126-37-0; Boc-piperazine-fluorobenzaldehyde derivative
EINECS	Contact for details

Quality Control

Our 4-(4-Boc-Piperazino-1-Yl)-3-Fluorobenzaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.