Description

2-(1,3-Dioxolan-2-On-4-Yl)-1-Ethylboronic Acid Pinacol Ester is a specialized organoboron compound, serving as a crucial protected boronic acid building block in advanced synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation, particularly in the synthesis of complex pharmaceutical intermediates and novel materials. This high-purity reagent is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality starting materials for Suzuki-Miyaura cross-coupling and other transition-metal-catalyzed reactions.

Application

• Pharmaceutical Intermediate Synthesis: A key precursor in the construction of active pharmaceutical ingredients (APIs) and complex drug candidates via cross-coupling methodologies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific boron-containing molecular architectures.
• Material Science & OLED Development: Employed in the synthesis of organic electronic materials, including ligands for metal-organic frameworks (MOFs) and emissive layers for organic light-emitting diodes (OLEDs).
• Academic & Industrial R&D: A valuable reagent for methodology development and exploring new chemical spaces in medicinal and synthetic chemistry laboratories.
• Fine Chemical Production: Facilitates the scalable synthesis of specialty chemicals and complex natural product analogs.
• Ligand & Catalyst Design: Serves as a building block for creating novel bidentate or polydentate ligands used in asymmetric catalysis.

Basic Information

Product Name	2-(1,3-Dioxolan-2-On-4-Yl)-1-Ethylboronic Acid Pinacol Ester
CAS No.	501014-47-7
Molecular Formula	C11H19BO5
Molecular Weight	242.08 g/mol
Synonyms	1-Ethyl-2-(1,3-dioxolan-2-on-4-yl)boronic Acid Pinacol Ester; 2-(1,3-Dioxolan-2-on-4-yl)-1-ethylboronic Acid Pinacol Ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-ethyl-1,3-dioxolan-2-one; 1-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dioxolan-2-one; (1-Ethyl-2-oxo-1,3-dioxolan-4-yl)boronic Acid Pinacol Ester; Boronic acid, B-[1-ethyl-2-oxo-1,3-dioxolan-4-yl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our 2-(1,3-Dioxolan-2-On-4-Yl)-1-Ethylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistent lot-to-lot performance critical for sensitive cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.